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  • enquiries@qiup.edu.my

Dr. Hema Ramachandran

Senior Lecturer,
School of Biological Sciences


  • Bsc (Hons) in Applied Biology (USM, 2009)
  • PhD in Microbial Biotechnology (USM, 2014)

Teaching and Research Experience:

  • Teaching – (April 2014 – Present) [QIUP]
  • Research – (2009 – Present)

Research Areas of Interests:

  • Production of biopolymer using bacteria, with particular emphasis on the P(3HB-co-4HB) copolymer and development of PHA based nanocomposites.
Administrative appointments / committee involvements
  • Secretariat Member of the Joint Committee on Issues Related to Biosafety/Animal Care, Use and Ethics/Human Research Ethics commencing from 1st June 2015.
  • Member of QIU Joint Research Ethics Committee
  • Course coordinator (Biochemistry 1 & 2, Fermentation Technology and Microbial Physiology)
  • Advisor of QIU Hindu Society (May 2015-May 2016)
On-going Research Projects
  • Fundamental Research Grant Scheme (FRGS)
  • Research title: Influence of glycerine pitch on the mechanism of regulation of 4HB monomer composition in the P(3HB-co-4HB) copolymer biosynthesis
  • Approved budget: RM 129 015
  1. Iszatty, I. Noor Aidda, O. Hema, R. and Amirul, A.A. (2017). Combination of 4-Hydroxybutyrate Carbon Precursors as Substrate for Simultaneous Production of P(3HB-co-4HB) and Yellow Pigment by Cupriavidus sp. USMAHM13. Arabian Journal for Science and Engineering, 42:2303-2311
  2. Ismail, I., Gurusamy, T.P., Ramachandran, H. and Amirul, A.A.-A. (2017). Enhanced production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) copolymer and antimicrobial yellow pigmentation from Cupriavidus sp. USMAHM13 with antibiofilm capability. Preparative Biochemistry and Biotechnology, 47:388-396.
  3. Shafie, N.A.H., Lau, N.-S., Ramachandran, H., Amirul, A.-A.A. (2017). Complete genome sequences of three Cupriavidus strains isolated from various Malaysian environments. Genome Announcement, 5:e01498-16
  4. Ramachandran, H., Iqbal, M.A. and Amirul, A.A. (2014) Identification and Characterization of the Yellow Pigment Synthesized by Cupriavidus sp. USMAHM13. Applied Biochemistry and Biotechnology, 174:461-470.
  5. Ramachandran, H. & Amirul, A.A. (2014). Bioconversion of glycerine pitch into a novel yellow-pigmented P(3HB-co-4HB) copolymer: Synergistic effect of ammonium acetate and polymer characteristics. Applied Biochemistry and Biotechnology, 172, 891-909.
  6. Ramachandran, H. & Amirul, A.A. (2013). Evaluation of unrefined glycerine pitch as an efficient renewable carbon resource for the biosynthesis of novel yellow-pigmented P(3HB-co-4HB) copolymer towards green technology. Biotechnology and Bioprocess Engineering, 18, 1250-1257.
  7. Ramachandran, H. & Amirul, A.A. (2013). Yellow-pigmented Cupriavidus sp., a novel bacterium capable of utilizing glycerine pitch for the sustainable production of P(3HB-co-4HB). Journal of Chemical Technology and Biotechnology, 88, 1030-1038.
  8. Hema, R., Ng, P.N. & Amirul, A.A. (2013). Green nanobiocomposite: reinforcement effect of montmorillonite clays on physical and biological advancement of various polyhydroxyalkanoates. Polymer Bulletin, 70, 755-771.
  9. Ramachandran H., Iqbal N. M., Sipaut C. S. & Amirul A. A. (2011). Biosynthesis and characterization of poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-4-hydroxybutyrate) terpolymer with various monomer compositions by Cupriavidus sp. USMAA2-4. Applied Biochemistry and Biotechnology, 164, 867-877.


  1. Amirul, A.-A., Ramachandran, H., Huong, K.-H. and Kannusamy, S. (2015). Microbial-based polyhydroxyalkanoates: Upstream and Downstream Processing. Smithers Rapra, United Kingdom.

Book Chapters:

  1. Shantini, K., Huong, K.-H., Ramachandran, H. and Amirul, A.A. (2015). Microbial production of polyhydroxyalkanoates for agricultural and aquacultural applications. In: M.-T. Liong (ed.). Beneficial microorganisms in agriculture, aquaculture and other areas. Switzerland: Springer International Publishing, 129-164.
  2. Ramachandran, H., Kannusamy, S., Huong, K.-H., Mathava, R. and Amirul, A.-A. (2014) Blends of polyhydroxyalkanoates (PHAs). In: Roy, I. and Visakh, P.M (eds). Natural polymers series: Polyhydroxyalkanoates (PHAs) based blends, composites and nanocomposites, United Kingdom: Royal Society of Chemistry, 66-97.
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